How Long Should You Take Nitazoxanide for Diarrhea?

Nitazoxanide is a broad-spectrum antiparasitic and antiviral medication commonly prescribed to treat diarrhea caused by specific intestinal infections.

Jul 12, 2025 - 11:33
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How Long Should You Take Nitazoxanide for Diarrhea?

Nitazoxanide 500 mgis a broad-spectrum antiparasitic and antiviral medication commonly prescribed to treat diarrhea caused by specific intestinal infections. Approved by health authorities for both adult and pediatric use, Nitazoxanide is especially effective against protozoan parasites likeGiardia lamblia and Cryptosporidium parvum. But how long should you take Nitazoxanide when dealing with diarrhea?

The duration of Nitazoxanide treatment depends on several factors: the cause of diarrhea, the age of the patient, and the severity of symptoms. This article offers a comprehensive guide to how long Nitazoxanide should be taken, its dosing schedule, and what patients should expect during the course of treatment.

? What Is Nitazoxanide?

Nitazoxanide 200 mgis an antiparasitic medication marketed under brand names likeAlinia, Nizonide, and others. It works by inhibiting the anaerobic energy metabolism of protozoa and some anaerobic bacteria, leading to their death and elimination from the body.

It is primarily prescribed for:

  • Giardiasis

  • Cryptosporidiosis

  • Chronic or acute diarrhea linked to protozoal infections

  • Occasionally used off-label for viral gastroenteritis and certain respiratory viruses

Nitazoxanide is available in tablet form (500 mg) for adults and oral suspension (100 mg/5 mL) for children.

? How Long Should You Take Nitazoxanide for Diarrhea?

The standard course of Nitazoxanide for diarrhea is generally 3 days, taken twice daily. However, this duration may vary based on the following factors:

? 1. Type of Infection

  • Giardiasis and cryptosporidiosis: 3-day course is typically effective

  • Viral gastroenteritis (off-label use): May require shorter or longer duration based on clinical judgment

  • Travelers diarrhea: Some cases may respond to a single-day or two-day treatment, depending on the pathogen

? 2. Age and Weight of the Patient

  • Children may require weight-based dosing over the same 3-day period.

  • Adults and adolescents above 12 years generally take 500 mg twice a day for 3 days.

? 3. Severity of Symptoms

  • If symptoms persist after the standard 3-day course, doctors may extend treatment to 57 days.

  • Severe cases or those with immune suppression (such as HIV-positive patients) may require longer monitoring and an extended course.

? Recommended Nitazoxanide Dosage Schedule

For Adults and Adolescents (?12 years):

  • 500 mg tablet, orally every 12 hours (twice daily) for 3 days

For Children (411 years):

  • 200 mg (10 mL oral suspension) every 12 hours for 3 days

For Children (13 years):

  • 100 mg (5 mL oral suspension) every 12 hours for 3 days

Important: Always follow your healthcare providers prescribed dosage. Do not self-medicate or change the schedule without professional guidance.

?? How to Take Nitazoxanide Properly

  • Take with food: Nitazoxanide is best absorbed when taken with a meal. This improves effectiveness and reduces stomach upset.

  • Use the full course: Even if symptoms improve after the first dose or two, complete the full course to ensure the infection is fully eliminated.

  • Stay hydrated: Diarrhea can lead to dehydration. Drinking fluids and using oral rehydration salts (ORS) may be necessary.

  • Shake oral suspension well before each use and use a dosing spoon for accuracy.

? What If You Miss a Dose?

If you miss a dose of Nitazoxanide:

  • Take it as soon as you remember

  • If its almost time for your next dose, skip the missed dosedont double up

  • Complete the entire course even if you feel better early

? When to See a Doctor

Sometimes, diarrhea may not improve with the standard treatment. Seek medical attention if:

  • Symptoms persist beyond 3 to 5 days

  • Diarrhea is accompanied by high fever, blood in stools, or severe dehydration

  • Youre immunocompromised or have a chronic illness

  • You experience side effects like rash, yellowing of the eyes, or severe abdominal pain

A stool test may be required to confirm if the infection has cleared or to adjust treatment.

? How Long Does Nitazoxanide Stay in Your System?

Nitazoxanide is rapidly metabolized in the body to its active form, tizoxanide, and has a half-life of around 13 hours. However, its effects can persist for longer due to its action on the parasites. After stopping treatment, the medication generally clears from the system within 12 days.

?? Side Effects to Watch For

Nitazoxanide is usually well tolerated, but some people may experience:

  • Nausea or vomiting

  • Abdominal pain

  • Headache

  • Yellowish urine (harmless)

  • Dizziness

Serious side effects are rare. Always report unexpected reactions to your doctor.

? Summary Table: Nitazoxanide for Diarrhea

Factor Recommendation
Standard Duration 3 days (twice daily)
Adult Dose 500 mg twice a day
Child Dose (13 yrs) 100 mg (5 mL) twice a day
Child Dose (411 yrs) 200 mg (10 mL) twice a day
With Food? Yes, take with food
Missed Dose? Take as soon as remembered
When to Seek Help? No improvement in 35 days, severe symptoms

In most cases, a 3-day course of Nitazoxanide is sufficient to treat diarrhea caused by protozoan parasites like Giardia and Cryptosporidium. For children and adults alike, proper dosing and taking the medicine with food are essential for success. If symptoms persist or worsen, dont extend or repeat the course without consulting your doctor. You can also Buy Nitazoxanide 200 mg Online from dosepharmacy.

Diarrhea can be a simple annoyance or a sign of something more serious. When treated properly with a medication like Nitazoxanide and monitored closely, recovery is usually quick and complete.

gracedosending Hello, I’m Grace Walker, a healthcare expert based in the USA, with four years of experience working at Dose Pharmacy, an online pharmacy. I specialize in women’s health, men’s health, skincare and infections, providing expert guidance and solutions to improve patient well-being through convenient and accessible healthcare services.